Involvement of the Rab27 Binding Protein Slac2c/MyRIP in Insulin Exocytosis

Rab27a is a GTPase associated with insulin-containing secretory granules of pancreatic β-cells. Selective reduction of Rab27a expression by RNA interference did not alter granule distribution and basal secretion but impaired exocytosis triggered by insulin secretagogues. Screening for potential effe...

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Autors principals: Waselle, Laurent, Coppola, Thierry, Fukuda, Mitsunori, Iezzi, Mariella, El-Amraoui, Aziz, Petit, Christine, Regazzi, Romano
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2003
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC207003/
https://ncbi.nlm.nih.gov/pubmed/14517322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-01-0022
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