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Involvement of the Rab27 Binding Protein Slac2c/MyRIP in Insulin Exocytosis
Rab27a is a GTPase associated with insulin-containing secretory granules of pancreatic β-cells. Selective reduction of Rab27a expression by RNA interference did not alter granule distribution and basal secretion but impaired exocytosis triggered by insulin secretagogues. Screening for potential effe...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC207003/ https://ncbi.nlm.nih.gov/pubmed/14517322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-01-0022 |
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