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Interaction between MyRIP and the actin cytoskeleton regulates Weibel–Palade body trafficking and exocytosis
Weibel–Palade body (WPB)–actin interactions are essential for the trafficking and secretion of von Willebrand factor; however, the molecular basis for this interaction remains poorly defined. Myosin Va (MyoVa or MYO5A) is recruited to WPBs by a Rab27A–MyRIP complex and is thought to be the prime med...
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| Publicado no: | J Cell Sci |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Ltd
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4760305/ https://ncbi.nlm.nih.gov/pubmed/26675235 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.178285 |
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