Interaction between MyRIP and the actin cytoskeleton regulates Weibel–Palade body trafficking and exocytosis

Weibel–Palade body (WPB)–actin interactions are essential for the trafficking and secretion of von Willebrand factor; however, the molecular basis for this interaction remains poorly defined. Myosin Va (MyoVa or MYO5A) is recruited to WPBs by a Rab27A–MyRIP complex and is thought to be the prime med...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Conte, Ianina L., Hellen, Nicola, Bierings, Ruben, Mashanov, Gregory I., Manneville, Jean-Baptiste, Kiskin, Nikolai I., Hannah, Matthew J., Molloy, Justin E., Carter, Tom
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760305/
https://ncbi.nlm.nih.gov/pubmed/26675235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.178285
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