Rab27a Is Required for Regulated Secretion in Cytotoxic T Lymphocytes

Rab27a activity is affected in several mouse models of human disease including Griscelli (ashen mice) and Hermansky-Pudlak (gunmetal mice) syndromes. A loss of function mutation occurs in the Rab27a gene in ashen (ash), whereas in gunmetal (gm) Rab27a dysfunction is secondary to a mutation in the α...

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Bibliographische Detailangaben
Hauptverfasser: Stinchcombe, Jane C., Barral, Duarte C., Mules, Emilie H., Booth, Sarah, Hume, Alistair N., Machesky, Laura M., Seabra, Miguel C., Griffiths, Gillian M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2001
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195783/
https://ncbi.nlm.nih.gov/pubmed/11266472
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