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A Coiled-Coil Domain of Melanophilin Is Essential for Myosin Va Recruitment and Melanosome Transport in Melanocytes

Melanophilin (Mlph) regulates retention of melanosomes at the peripheral actin cytoskeleton of melanocytes, a process essential for normal mammalian pigmentation. Mlph is proposed to be a modular protein binding the melanosome-associated protein Rab27a, Myosin Va (MyoVa), actin, and microtubule end-...

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Hlavní autoři: Hume, Alistair N., Tarafder, Abul K., Ramalho, José S., Sviderskaya, Elena V., Seabra, Miguel C.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635380/
https://ncbi.nlm.nih.gov/pubmed/16914517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-05-0457
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