Minireview: The Effects of Species Ortholog and SNP Variation on Receptors for Free Fatty Acids

od Hudson, Brian D., Murdoch, Hannah, Milligan, Graeme
Wydane 2013

Physical and functional interaction between CB(1) cannabinoid receptors and β(2)-adrenoceptors

od Hudson, Brian D, Hébert, Terence E, Kelly, Melanie EM
Wydane 2010

The Molecular Basis of Ligand Interaction at Free Fatty Acid Receptor 4 (FFA4/GPR120)

od Hudson, Brian D., Shimpukade, Bharat, Milligan, Graeme, Ulven, Trond
Wydane 2014

Treatment of Type 2 Diabetes by Free Fatty Acid Receptor Agonists

od Watterson, Kenneth R., Hudson, Brian D., Ulven, Trond, Milligan, Graeme
Wydane 2014

Extracellular Ionic Locks Determine Variation in Constitutive Activity and Ligand Potency between Species Orthologs of the Free Fatty Acid Receptors FFA2 and FFA3

od Hudson, Brian D., Tikhonova, Irina G., Pandey, Sunil K., Ulven, Trond, Milligan, Graeme
Wydane 2012

FFA4/GPR120: Pharmacology and Therapeutic Opportunities

od Milligan, Graeme, Alvarez-Curto, Elisa, Hudson, Brian D., Prihandoko, Rudi, Tobin, Andrew B.
Wydane w Trends Pharmacol Sci (2017)

Chemically engineering ligand selectivity at the free fatty acid receptor 2 based on pharmacological variation between species orthologs

od Hudson, Brian D., Christiansen, Elisabeth, Tikhonova, Irina G., Grundmann, Manuel, Kostenis, Evi, Adams, David R., Ulven, Trond, Milligan, Graeme
Wydane 2012

Non-equivalence of Key Positively Charged Residues of the Free Fatty Acid 2 Receptor in the Recognition and Function of Agonist Versus Antagonist Ligands

od Sergeev, Eugenia, Hansen, Anders Højgaard, Pandey, Sunil K., MacKenzie, Amanda E., Hudson, Brian D., Ulven, Trond, Milligan, Graeme
Wydane w J Biol Chem (2016)

Concomitant Action of Structural Elements and Receptor Phosphorylation Determines Arrestin-3 Interaction with the Free Fatty Acid Receptor FFA4

od Butcher, Adrian J., Hudson, Brian D., Shimpukade, Bharat, Alvarez-Curto, Elisa, Prihandoko, Rudi, Ulven, Trond, Milligan, Graeme, Tobin, Andrew B.
Wydane 2014

Mechanism and Function of Drosophila capa GPCR: A Desiccation Stress-Responsive Receptor with Functional Homology to Human NeuromedinU Receptor

od Terhzaz, Selim, Cabrero, Pablo, Robben, Joris H., Radford, Jonathan C., Hudson, Brian D., Milligan, Graeme, Dow, Julian A. T., Davies, Shireen-A.
Wydane 2012

A single extracellular amino acid in Free Fatty Acid Receptor 2 defines antagonist species selectivity and G protein selection bias

od Sergeev, Eugenia, Hansen, Anders Højgaard, Bolognini, Daniele, Kawakami, Kouki, Kishi, Takayuki, Aoki, Junken, Ulven, Trond, Inoue, Asuka, Hudson, Brian D., Milligan, Graeme
Wydane w Sci Rep (2017)

Three classes of ligands each bind to distinct sites on the orphan G protein-coupled receptor GPR84

od Mahmud, Zobaer Al, Jenkins, Laura, Ulven, Trond, Labéguère, Frédéric, Gosmini, Romain, De Vos, Steve, Hudson, Brian D., Tikhonova, Irina G., Milligan, Graeme
Wydane w Sci Rep (2017)

The Pharmacology of TUG-891, a Potent and Selective Agonist of the Free Fatty Acid Receptor 4 (FFA4/GPR120), Demonstrates Both Potential Opportunity and Possible Challenges to Ther...

od Hudson, Brian D., Shimpukade, Bharat, Mackenzie, Amanda E., Butcher, Adrian J., Pediani, John D., Christiansen, Elisabeth, Heathcote, Helen, Tobin, Andrew B., Ulven, Trond, Milligan, Graeme
Wydane 2013

Receptor selectivity between the G proteins Gα(12) and Gα(13) is defined by a single leucine-to-isoleucine variation

od Mackenzie, Amanda E., Quon, Tezz, Lin, Li-Chiung, Hauser, Alexander S., Jenkins, Laura, Inoue, Asuka, Tobin, Andrew B., Gloriam, David E., Hudson, Brian D., Milligan, Graeme
Wydane w FASEB J (2019)

Selective Orthosteric Free Fatty Acid Receptor 2 (FFA2) Agonists: IDENTIFICATION OF THE STRUCTURAL AND CHEMICAL REQUIREMENTS FOR SELECTIVE ACTIVATION OF FFA2 VERSUS FFA3

od Schmidt, Johannes, Smith, Nicola J., Christiansen, Elisabeth, Tikhonova, Irina G., Grundmann, Manuel, Hudson, Brian D., Ward, Richard J., Drewke, Christel, Milligan, Graeme, Kostenis, Evi, Ulven, Trond
Wydane 2011

Extracellular Loop 2 of the Free Fatty Acid Receptor 2 Mediates Allosterism of a Phenylacetamide Ago-Allosteric Modulator

od Smith, Nicola J., Ward, Richard J., Stoddart, Leigh A., Hudson, Brian D., Kostenis, Evi, Ulven, Trond, Morris, Joanne C., Tränkle, Christian, Tikhonova, Irina G., Adams, David R., Milligan, Graeme
Wydane 2011

The Antiallergic Mast Cell Stabilizers Lodoxamide and Bufrolin as the First High and Equipotent Agonists of Human and Rat GPR35

od MacKenzie, Amanda E., Caltabiano, Gianluigi, Kent, Toby C., Jenkins, Laura, McCallum, Jennifer E., Hudson, Brian D., Nicklin, Stuart A., Fawcett, Lindsay, Markwick, Rachel, Charlton, Steven J., Milligan, Graeme
Wydane 2014

Probe-Dependent Negative Allosteric Modulators of the Long-Chain Free Fatty Acid Receptor FFA4

od Watterson, Kenneth R., Hansen, Steffen V. F., Hudson, Brian D., Alvarez-Curto, Elisa, Raihan, Sheikh Zahir, Azevedo, Carlos M. G., Martin, Gabriel, Dunlop, Julia, Yarwood, Stephen J., Ulven, Trond, Milligan, Graeme
Wydane w Mol Pharmacol (2017)

Defining the Molecular Basis for the First Potent and Selective Orthosteric Agonists of the FFA2 Free Fatty Acid Receptor

od Hudson, Brian D., Due-Hansen, Maria E., Christiansen, Elisabeth, Hansen, Anna Mette, Mackenzie, Amanda E., Murdoch, Hannah, Pandey, Sunil K., Ward, Richard J., Marquez, Rudi, Tikhonova, Irina G., Ulven, Trond, Milligan, Graeme
Wydane 2013

Structure–Activity Relationship Studies of Tetrahydroquinolone Free Fatty Acid Receptor 3 Modulators

od Ulven, Elisabeth Rexen, Quon, Tezz, Sergeev, Eugenia, Barki, Natasja, Brvar, Matjaz, Hudson, Brian D., Dutta, Palash, Hansen, Anders Højgaard, Bielefeldt, Line Ø., Tobin, Andrew B., McKenzie, Christine J., Milligan, Graeme, Ulven, Trond
Wydane w J Med Chem (2020)