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Structure–Activity Relationship Studies of Tetrahydroquinolone Free Fatty Acid Receptor 3 Modulators

[Image: see text] Free fatty acid receptor 3 (FFA3, previously GPR41) is activated by short-chain fatty acids, mediates health effects of the gut microbiota, and is a therapeutic target for metabolic and inflammatory diseases. The shortage of well-characterized tool compounds has however impeded pro...

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Detalhes bibliográficos
Publicado no:J Med Chem
Main Authors: Ulven, Elisabeth Rexen, Quon, Tezz, Sergeev, Eugenia, Barki, Natasja, Brvar, Matjaz, Hudson, Brian D., Dutta, Palash, Hansen, Anders Højgaard, Bielefeldt, Line Ø., Tobin, Andrew B., McKenzie, Christine J., Milligan, Graeme, Ulven, Trond
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7307922/
https://ncbi.nlm.nih.gov/pubmed/32141297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.9b02036
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