Structure–Activity Relationship Studies of Tetrahydroquinolone Free Fatty Acid Receptor 3 Modulators

[Image: see text] Free fatty acid receptor 3 (FFA3, previously GPR41) is activated by short-chain fatty acids, mediates health effects of the gut microbiota, and is a therapeutic target for metabolic and inflammatory diseases. The shortage of well-characterized tool compounds has however impeded pro...

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Publicat a:J Med Chem
Autors principals: Ulven, Elisabeth Rexen, Quon, Tezz, Sergeev, Eugenia, Barki, Natasja, Brvar, Matjaz, Hudson, Brian D., Dutta, Palash, Hansen, Anders Højgaard, Bielefeldt, Line Ø., Tobin, Andrew B., McKenzie, Christine J., Milligan, Graeme, Ulven, Trond
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2020
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7307922/
https://ncbi.nlm.nih.gov/pubmed/32141297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.9b02036
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