Probe-Dependent Negative Allosteric Modulators of the Long-Chain Free Fatty Acid Receptor FFA4

High-affinity and selective antagonists that are able to block the actions of both endogenous and synthetic agonists of G protein–coupled receptors are integral to analysis of receptor function and to support suggestions of therapeutic potential. Although there is great interest in the potential of...

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Publicat a:Mol Pharmacol
Autors principals: Watterson, Kenneth R., Hansen, Steffen V. F., Hudson, Brian D., Alvarez-Curto, Elisa, Raihan, Sheikh Zahir, Azevedo, Carlos M. G., Martin, Gabriel, Dunlop, Julia, Yarwood, Stephen J., Ulven, Trond, Milligan, Graeme
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Pharmacology and Experimental Therapeutics 2017
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5438128/
https://ncbi.nlm.nih.gov/pubmed/28385906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.116.107821
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