Characterizing pharmacological ligands to study the long-chain fatty acid receptors GPR40/FFA1 and GPR120/FFA4

The free fatty acid receptors (FFA) 1 (previously designated GPR40) and FFA4 (previously GPR120) are two GPCRs activated by saturated and unsaturated longer-chain free fatty acids. With expression patterns and functions anticipated to directly or indirectly promote insulin secretion, provide homeost...

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Bibliografiske detaljer
Udgivet i:Br J Pharmacol
Main Authors: Milligan, G, Alvarez-Curto, E, Watterson, K R, Ulven, T, Hudson, B D
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Ltd 2015
Fag:
Themed Section: 5TH Bps Focused Meeting on Cell Signalling
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4500364/
https://ncbi.nlm.nih.gov/pubmed/25131623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12879
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