Inhibiting Gene Expression with Peptide Nucleic Acid (PNA)–Peptide Conjugates that Target Chromosomal DNA

Por Hu, Jiaxin, Corey, David R.
Publicado em 2007

Allele-selective inhibition of huntingtin expression by switching to an miRNA-like RNAi mechanism

Por Hu, Jiaxin, Liu, Jing, Corey, David R.
Publicado em 2010

Expanding the action of duplex RNAs into the nucleus: redirecting alternative splicing

Por Liu, Jing, Hu, Jiaxin, Corey, David R.
Publicado em 2012

Allele-Selective Inhibition of Mutant Huntingtin by Peptide Nucleic Acid (PNA)-Peptide Conjugates, Locked Nucleic Acid (LNA), and siRNA

Por Hu, Jiaxin, Matsui, Masayuki, Corey, David R.
Publicado em 2009

Probing alkali metal–π interactions with the side chain residue of tryptophan

Por Hu, Jiaxin, Barbour, Leonard J., Gokel, George W.
Publicado em 2002

Recognition of c9orf72 Mutant RNA by Single-Stranded Silencing RNAs

Por Hu, Jiaxin, Rigo, Frank, Prakash, Thazha P., Corey, David R.
Publicado no Nucleic Acid Ther (2017)

Mechanism of allele-selective inhibition of huntingtin expression by duplex RNAs that target CAG repeats: function through the RNAi pathway

Por Hu, Jiaxin, Liu, Jing, Yu, Dongbo, Chu, Yongjun, Corey, David R.
Publicado em 2012

Engineering Duplex RNAs for Challenging Targets: Recognition of GGGGCC/CCCCGG repeats at the ALS/FTD C9orf72 locus

Por Hu, Jiaxin, Liu, Jing, Li, Liande, Gagnon, Keith T., Corey, David R.
Publicado no Chem Biol (2015)

Cellular localization and allele-selective inhibition of mutant huntingtin protein by peptide nucleic acid oligomers containing the fluorescent nucleobase [bis-o-(aminoethoxy)pheny...

Por Hu, Jiaxin, Dodd, David W., Hudson, Robert H. E., Corey, David R.
Publicado em 2009

Allele-Selective Inhibition of Huntingtin and Ataxin-3 Expression by RNA Duplexes Containing Unlocked Nucleic Acid (UNA) Substitutions

Por Aiba, Yuichiro, Hu, Jiaxin, Liu, Jing, Xiang, Qin, Martinez, Carlos, Corey, David R.
Publicado em 2013

Modulation of Splicing by Single-Stranded Silencing RNAs

Por Liu, Jing, Hu, Jiaxin, Hicks, Jessica A., Prakash, Thazha P., Corey, David R.
Publicado no Nucleic Acid Ther (2015)

c9orf72 Disease-Related Foci are Each Composed of One Mutant Expanded Repeat RNA

Por Liu, Jing, Hu, Jiaxin, Ludlow, Andrew, Pham, Jackie, Shay, Jerry W., Rothstein, Jeffrey D., Corey, David R.
Publicado no Cell Chem Biol (2017)

Inhibiting Expression of Mutant Huntingtin and Ataxin-3 by Targeting Expanded CAG Repeat RNAs

Por Hu, Jiaxin, Matsui, Masayuki, Gagnon, Keith T., Schwartz, Jacob C., Gabillet, Sylvie, Arar, Khalil, Wu, Jun, Bezprozvanny, Ilya, Corey, David R.
Publicado em 2009

ss-siRNAs allele selectively inhibit ataxin-3 expression: multiple mechanisms for an alternative gene silencing strategy

Por Liu, Jing, Yu, Dongbo, Aiba, Yuichiro, Pendergraff, Hannah, Swayze, Eric E., Lima, Walt F., Hu, Jiaxin, Prakash, Thazha P., Corey, David R.
Publicado em 2013

RNA duplexes with abasic substitutions are potent and allele-selective inhibitors of huntingtin and ataxin-3 expression

Por Liu, Jing, Pendergraff, Hannah, Narayanannair, K. Jayaprakash, Lackey, Jeremy G., Kuchimanchi, Satya, Rajeev, Kallanthottathil G., Manoharan, Muthiah, Hu, Jiaxin, Corey, David R.
Publicado em 2013

Allele-selective inhibition of ataxin-3 (ATX3) expression by antisense oligomers and duplex RNAs

Por Hu, Jiaxin, Gagnon, Keith T., Liu, Jing, Watts, Jonathan K., Syeda-Nawaz, Jeja, Bennett, C. Frank, Swayze, Eric E., Randolph, John, Chattopadhyaya, Jyoti, Corey, David R.
Publicado em 2011

Exploring the Effect of Sequence Length and Composition on Allele-Selective Inhibition of Human Huntingtin Expression by Single-Stranded Silencing RNAs

Por Hu, Jiaxin, Liu, Jing, Yu, Dongbo, Aiba, Yuichiro, Lee, Suheung, Pendergraff, Hannah, Boubaker, Jihane, Artates, Jonathan W., Lagier-Tourenne, Clotilde, Lima, Walt F., Swayze, Eric E., Prakash, Thazha P., Corey, David R.
Publicado em 2014

Allele-Selective Inhibition of Mutant Atrophin-1 Expression by Duplex and Single-Stranded RNAs

Por Hu, Jiaxin, Liu, Jing, Narayanannair, K. Jayaprakash, Lackey, Jeremy G., Kuchimanchi, Satya, Rajeev, Kallanthottathil G., Manoharan, Muthiah, Swayze, Eric E., Lima, Walt F., Prakash, Thazha P., Xiang, Qin, Martinez, Carlos, Corey, David R.
Publicado em 2014

Peptide Nucleic Acids Conjugated to Short Basic Peptides Show Improved Pharmacokinetics and Antisense Activity in Adipose Tissue

Por Wancewicz, Edward V., Maier, Martin A., Siwkowski, Andrew M., Albertshofer, Klaus, Winger, Theodore M., Berdeja, Andres, Gaus, Hans, Vickers, Timothy A., Bennett, C. Frank, Monia, Brett P., Griffey, Richard H., Nulf, Christopher J., Hu, Jiaxin, Corey, David R., Swayze, Eric E., Kinberger, Garth A.
Publicado em 2010