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Duplex RNAs and ss-siRNAs Block RNA Foci Associated with Fuchs' Endothelial Corneal Dystrophy

Fuchs' endothelial corneal dystrophy (FECD) leads to vision loss and is one of the most common inherited eye diseases. Corneal transplants are the only curative treatment available, and there is a major unmet need for treatments that are less invasive and independent of donor tissue. Most cases...

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Библиографические подробности
Опубликовано в: :Nucleic Acid Ther
Главные авторы: Hu, Jiaxin, Shen, Xiulong, Rigo, Frank, Prakash, Thahza P., Mootha, V. Vinod, Corey, David R.
Формат: Artigo
Язык:Inglês
Опубликовано: Mary Ann Liebert, Inc., publishers 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461152/
https://ncbi.nlm.nih.gov/pubmed/30676271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2018.0764
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