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Expanding the action of duplex RNAs into the nucleus: redirecting alternative splicing

Double-stranded RNAs are powerful agents for silencing gene expression in the cytoplasm of mammalian cells. The potential for duplex RNAs to control expression in the nucleus has received less attention. Here, we investigate the ability of small RNAs to redirect splicing. We identify RNAs targeting...

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Bibliografske podrobnosti
Main Authors: Liu, Jing, Hu, Jiaxin, Corey, David R.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2012
Teme:
RNA
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273794/
https://ncbi.nlm.nih.gov/pubmed/21948593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr780
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