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Expanding the action of duplex RNAs into the nucleus: redirecting alternative splicing

Double-stranded RNAs are powerful agents for silencing gene expression in the cytoplasm of mammalian cells. The potential for duplex RNAs to control expression in the nucleus has received less attention. Here, we investigate the ability of small RNAs to redirect splicing. We identify RNAs targeting...

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Detalhes bibliográficos
Main Authors: Liu, Jing, Hu, Jiaxin, Corey, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273794/
https://ncbi.nlm.nih.gov/pubmed/21948593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr780
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