Loading...
Allele-selective inhibition of huntingtin expression by switching to an miRNA-like RNAi mechanism
Inhibiting expression of huntingtin (HTT) protein is a promising strategy for treating Huntington’s Disease (HD), but indiscriminant inhibition of both wild-type and mutant alleles may lead to toxicity. An ideal silencing agent would block expression of mutant HTT while leaving expression of wild-ty...
Na minha lista:
| Main Authors: | , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3021381/ https://ncbi.nlm.nih.gov/pubmed/21095568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2010.10.013 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|