Llwytho...
Single-Stranded RNAs Use RNAi to Potently and Allele-Selectively Inhibit Mutant Huntingtin Expression
Mutant huntingtin (HTT) protein causes Huntington’s Disease (HD), an incurable neurological disorder. Silencing mutant HTT using nucleic acids would eliminate the root cause of HD. Developing nucleic acid drugs is challenging, and an ideal clinical approach to gene silencing would combine the simpli...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , , , , , , |
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| Fformat: | Artigo |
| Iaith: | Inglês |
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2012
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| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3444165/ https://ncbi.nlm.nih.gov/pubmed/22939619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.08.002 |
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