Cellular localization and allele-selective inhibition of mutant huntingtin protein by peptide nucleic acid oligomers containing the fluorescent nucleobase [bis-o-(aminoethoxy)phenyl]pyrrolocytosine

Peptide nucleic acid (PNA) is a successful DNA/RNA mimic. A major challenge for research is to invent chemically modified PNAs that retain the favorable properties of the parent compound while improving biological recognition. Here we test modified PNAs containing [bis-o-(aminoethoxy)phenyl]pyrroloc...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Hu, Jiaxin, Dodd, David W., Hudson, Robert H. E., Corey, David R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770837/
https://ncbi.nlm.nih.gov/pubmed/19783436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2009.09.004
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky