Elucidating the mechanism of familial amyloidosis– Finnish type: NMR studies of human gelsolin domain 2

Por Kazmirski, Steven L., Howard, Mark J., Isaacson, Rivka L., Fersht, Alan R.
Publicado em 2000

Structural Definition Is Important for the Propagation of the Yeast [PSI(+)] Prion

Por Marchante, Ricardo, Rowe, Michelle, Zenthon, Jo, Howard, Mark J., Tuite, Mick F.
Publicado em 2013

Optimising selective excitation pulses to maximise saturation transfer difference NMR spectroscopy

Por Ley, Nathan B., Rowe, Michelle L., Williamson, Richard A., Howard, Mark J.
Publicado no RSC Adv (2014)

Conserved differences in protein sequence determine the human pathogenicity of Ebolaviruses

Por Pappalardo, Morena, Juliá, Miguel, Howard, Mark J., Rossman, Jeremy S., Michaelis, Martin, Wass, Mark N.
Publicado no Sci Rep (2016)

Membrane remodeling by the M2 amphipathic helix drives influenza virus membrane scission

Por Martyna, Agnieszka, Bahsoun, Basma, Badham, Matthew D., Srinivasan, Saipraveen, Howard, Mark J., Rossman, Jeremy S.
Publicado no Sci Rep (2017)

(1)H NMR Spectroscopy Profiling of Metabolic Reprogramming of Chinese Hamster Ovary Cells upon a Temperature Shift during Culture

Por Wagstaff, Jane L., Masterton, Rosalyn J., Povey, Jane F., Smales, C. Mark, Howard, Mark J.
Publicado em 2013

Q2DSTD NMR deciphers epitope-mapping variability for peptide recognition of integrin αvβ6

Por Sorge, Jessica L., Wagstaff, Jane L., Rowe, Michelle L., Williamson, Richard A., Howard, Mark J.
Publicado no Org Biomol Chem (2015)

Combined ligand-observe (19)F and protein-observe (15)N,(1)H-HSQC NMR suggests phenylalanine as the key Δ-somatostatin residue recognized by human protein disulfide isomerase

Por Richards, Kirsty L., Rowe, Michelle L., Hudson, Paul B., Williamson, Richard A., Howard, Mark J.
Publicado no Sci Rep (2016)

(19)F NMR spectroscopy monitors ligand binding to recombinantly fluorine-labelled b′x from human protein disulphide isomerase (hPDI)

Por Curtis-Marof, Rose, Doko, Denisa, Rowe, Michelle L., Richards, Kirsty L., Williamson, Richard A., Howard, Mark J.
Publicado em 2014

New insights into stop codon recognition by eRF1

Por Blanchet, Sandra, Rowe, Michelle, Von der Haar, Tobias, Fabret, Céline, Demais, Stéphane, Howard, Mark J., Namy, Olivier
Publicado no Nucleic Acids Res (2015)

Inappropriate expression of the translation elongation factor 1A disrupts genome stability and metabolism

Por Tarrant, Daniel J., Stirpe, Mariarita, Rowe, Michelle, Howard, Mark J., von der Haar, Tobias, Gourlay, Campbell W.
Publicado no J Cell Sci (2016)

Foot-and-Mouth Disease Virus Forms a Highly Stable, EDTA-Resistant Complex with Its Principal Receptor, Integrin αvβ6: Implications for Infectiousness

Por DiCara, Danielle, Burman, Alison, Clark, Stuart, Berryman, Stephen, Howard, Mark J., Hart, Ian R., Marshall, John F., Jackson, Terry
Publicado em 2008

The ligand-binding b′ domain of human protein disulphide-isomerase mediates homodimerization

Por Wallis, Anne Katrine, Sidhu, Ateesh, Byrne, Lee J, Howard, Mark J, Ruddock, Lloyd W, Williamson, Richard A, Freedman, Robert B
Publicado em 2009

Characterization of the Enzyme CbiH(60) Involved in Anaerobic Ring Contraction of the Cobalamin (Vitamin B(12)) Biosynthetic Pathway

Por Moore, Simon J., Biedendieck, Rebekka, Lawrence, Andrew D., Deery, Evelyne, Howard, Mark J., Rigby, Stephen E. J., Warren, Martin J.
Publicado em 2013

High-resolution NMR studies of structure and dynamics of human ERp27 indicate extensive interdomain flexibility

Por Amin, Nader T., Wallis, A. Katrine, Wells, Stephen A., Rowe, Michelle L., Williamson, Richard A., Howard, Mark J., Freedman, Robert B.
Publicado em 2013

Measuring protein reduction potentials using (15)N HSQC NMR spectroscopy()

Por Taylor, Samantha L., Crawley-Snowdon, Harriet, Wagstaff, Jane L., Rowe, Michelle L., Shepherd, Mark, Williamson, Richard A., Howard, Mark J.
Publicado no Chem Commun (Camb) (2013)

CydDC-mediated reductant export in Escherichia coli controls the transcriptional wiring of energy metabolism and combats nitrosative stress

Por Holyoake, Louise V., Hunt, Stuart, Sanguinetti, Guido, Cook, Gregory M., Howard, Mark J., Rowe, Michelle L., Poole, Robert K., Shepherd, Mark
Publicado no Biochem J (2016)

NMR relaxation and structural elucidation of peptides in the presence and absence of trifluoroethanol illuminates the critical molecular nature of integrin αvβ6 ligand specificity...

Por Wagstaff, Jane L., Rowe, Michelle L., Hsieh, Shu-Ju, DiCara, Danielle, Marshall, John F., Williamson, Richard A., Howard, Mark J.
Publicado no RSC Adv (2012)

Elucidation of the anaerobic pathway for the corrin component of cobalamin (vitamin B(12))

Por Moore, Simon J., Lawrence, Andrew D., Biedendieck, Rebekka, Deery, Evelyne, Frank, Stefanie, Howard, Mark J., Rigby, Stephen E. J., Warren, Martin J.
Publicado em 2013

The Fanconi Anemia DNA Repair Pathway Is Regulated by an Interaction between Ubiquitin and the E2-like Fold Domain of FANCL

Por Miles, Jennifer A., Frost, Mark G., Carroll, Eilis, Rowe, Michelle L., Howard, Mark J., Sidhu, Ateesh, Chaugule, Viduth K., Alpi, Arno F., Walden, Helen
Publicado no J Biol Chem (2015)