CydDC-mediated reductant export in Escherichia coli controls the transcriptional wiring of energy metabolism and combats nitrosative stress

The glutathione/cysteine exporter CydDC maintains redox balance in Escherichia coli. A cydD mutant strain was used to probe the influence of CydDC upon reduced thiol export, gene expression, metabolic perturbations, intracellular pH homoeostasis and tolerance to nitric oxide (NO). Loss of CydDC was...

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Pubblicato in:Biochem J
Autori principali: Holyoake, Louise V., Hunt, Stuart, Sanguinetti, Guido, Cook, Gregory M., Howard, Mark J., Rowe, Michelle L., Poole, Robert K., Shepherd, Mark
Natura: Artigo
Lingua:Inglês
Pubblicazione: Portland Press Ltd. 2016
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4785604/
https://ncbi.nlm.nih.gov/pubmed/26699904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20150536
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