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Structural Definition Is Important for the Propagation of the Yeast [PSI(+)] Prion
Prions are propagated in Saccharomyces cerevisiae with remarkable efficiency, yet we know little about the structural basis of sequence variations in the prion protein that support or prohibit propagation of the prion conformation. We show that certain single-amino-acid substitutions in the prion pr...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cell Press
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3679450/ https://ncbi.nlm.nih.gov/pubmed/23746351 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.05.010 |
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