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Probing the role of structural features of mouse PrP in yeast by expression as Sup35-PrP fusions
The yeast Saccharomyces cerevisiae is a tractable model organism in which both to explore the molecular mechanisms underlying the generation of disease-associated protein misfolding and to map the cellular responses to potentially toxic misfolded proteins. Specific targets have included proteins whi...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Landes Bioscience
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3399540/ https://ncbi.nlm.nih.gov/pubmed/22449853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.19214 |
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