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Probing the role of structural features of mouse PrP in yeast by expression as Sup35-PrP fusions

The yeast Saccharomyces cerevisiae is a tractable model organism in which both to explore the molecular mechanisms underlying the generation of disease-associated protein misfolding and to map the cellular responses to potentially toxic misfolded proteins. Specific targets have included proteins whi...

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Hlavní autoři: Jossé, Lyne, Marchante, Ricardo, Zenthon, Jo, von der Haar, Tobias, Tuite, Mick F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3399540/
https://ncbi.nlm.nih.gov/pubmed/22449853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.19214
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