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Probing the Role of PrP Repeats in Conformational Conversion and Amyloid Assembly of Chimeric Yeast Prions

Oligopeptide repeats appear in many proteins that undergo conformational conversions to form amyloid, including the mammalian prion protein PrP and the yeast prion protein Sup35. Whereas the repeats in PrP have been studied more exhaustively, interpretation of these studies is confounded by the fact...

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Detalles Bibliográficos
Main Authors: Dong, Jijun, Bloom, Jesse D., Goncharov, Vladimir, Chattopadhyay, Madhuri, Millhauser, Glenn L., Lynn, David G., Scheibel, Thomas, Lindquist, Susan
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2262835/
https://ncbi.nlm.nih.gov/pubmed/17893150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M704952200
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