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Strain conformation, primary structure and the propagation of the yeast prion [PSI(+)]

Prion proteins can adopt multiple different infectious strain conformations. Here we examine how the sequence of a prion protein affects its capacity to propagate specific conformations by exploiting our ability to create two distinct infectious conformations of the yeast [PSI(+)] prion protein Sup3...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Verges, Katherine J., Smith, Melanie H., Toyama, Brandon H., Weissman, Jonathan S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3490428/
https://ncbi.nlm.nih.gov/pubmed/21423194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2030
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