Specificity and disease in the ubiquitin system

Por Chaugule, Viduth K., Walden, Helen
Publicado no Biochem Soc Trans (2016)

Small, N-Terminal Tags Activate Parkin E3 Ubiquitin Ligase Activity by Disrupting Its Autoinhibited Conformation

Por Burchell, Lynn, Chaugule, Viduth K., Walden, Helen
Publicado em 2012

Autoregulation of Parkin activity through its ubiquitin-like domain

Por Chaugule, Viduth K, Burchell, Lynn, Barber, Kathryn R, Sidhu, Ateesh, Leslie, Simon J, Shaw, Gary S, Walden, Helen
Publicado em 2011

The Fanconi Anemia DNA Repair Pathway Is Regulated by an Interaction between Ubiquitin and the E2-like Fold Domain of FANCL

Por Miles, Jennifer A., Frost, Mark G., Carroll, Eilis, Rowe, Michelle L., Howard, Mark J., Sidhu, Ateesh, Chaugule, Viduth K., Alpi, Arno F., Walden, Helen
Publicado no J Biol Chem (2015)

Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis

Por Kumar, Atul, Aguirre, Jacob D, Condos, Tara EC, Martinez-Torres, R Julio, Chaugule, Viduth K, Toth, Rachel, Sundaramoorthy, Ramasubramanian, Mercier, Pascal, Knebel, Axel, Spratt, Donald E, Barber, Kathryn R, Shaw, Gary S, Walden, Helen
Publicado no EMBO J (2015)