Regulation of DNA Damage Following Termination of Hedgehog (HH) Survival Signaling at the level of the GLI Genes in Human Colon Cancer

Por Agyeman, Akwasi, Mazumdar, Tapati, Houghton, Janet A.
Publicado em 2012

Thymineless death in colon carcinoma cells is mediated via Fas signaling

Por Houghton, Janet A., Harwood, Franklin G., Tillman, David M.
Publicado em 1997

Mode and specificity of binding of the small molecule GANT61 to GLI determines inhibition of GLI-DNA binding

Por Agyeman, Akwasi, Jha, Babal K, Mazumdar, Tapati, Houghton, Janet A
Publicado em 2014

Inhibition of NF-κB Signaling by Quinacrine Is Cytotoxic to Human Colon Carcinoma Cell Lines and Is Synergistic in Combination with Tumor Necrosis Factor-related Apoptosis-inducing...

Por Jani, Tanvi S., DeVecchio, Jennifer, Mazumdar, Tapati, Agyeman, Akwasi, Houghton, Janet A.
Publicado em 2010

Identification of STAT3-independent regulatory effects for protein inhibitor of activated STAT3 by binding to novel transcription factors

Por Dabir, Snehal, Kluge, Amy, Aziz, Mohammad A, Houghton, Janet A, Dowlati, Afshin
Publicado em 2011

Blocking Hedgehog survival signaling at the level of the GLI genes induces DNA damage and extensive cell death in human colon carcinoma cells

Por Mazumdar, Tapati, DeVecchio, Jennifer, Agyeman, Akwasi, Shi, Ting, Houghton, Janet A.
Publicado em 2011

The GLI genes as the molecular switch in disrupting Hedgehog signaling in colon cancer

Por Mazumdar, Tapati, DeVecchio, Jennifer, Agyeman, Akwasi, Shi, Ting, Houghton, Janet A.
Publicado em 2011

Targeting GLI by GANT61 involves mechanisms dependent on inhibition of both transcription and DNA licensing

Por Zhang, Ruowen, Wu, Jiahui, Ferrandon, Sylvain, Glowacki, Katie J., Houghton, Janet A.
Publicado no Oncotarget (2016)

Hedgehog signaling drives cellular survival in human colon carcinoma cells

Por Mazumdar, Tapati, DeVecchio, Jennifer, Shi, Ting, Jones, Janay, Agyeman, Akwasi, Houghton, Janet A.
Publicado em 2010

ATP modulates PTEN subcellular localization in multiple cancer cell lines

Por Lobo, Glenn P., Waite, Kristin A., Planchon, Sarah M., Romigh, Todd, Houghton, Janet A., Eng, Charis
Publicado em 2008

cDNA Microarray Gene Expression Profiling of Hedgehog Signaling Pathway Inhibition in Human Colon Cancer Cells

Por Shi, Ting, Mazumdar, Tapati, DeVecchio, Jennifer, Duan, Zhong-Hui, Agyeman, Akwasi, Aziz, Mohammad, Houghton, Janet A.
Publicado em 2010

FOXO1a acts as a selective tumor suppressor in alveolar rhabdomyosarcoma

Por Bois, Philippe R.J., Izeradjene, Kamel, Houghton, Peter J., Cleveland, John L., Houghton, Janet A., Grosveldz, Gerard C.
Publicado em 2007

FOXO1a acts as a selective tumor suppressor in alveolar rhabdomyosarcoma

Por Bois, Philippe R.J., Izeradjene, Kamel, Houghton, Peter J., Cleveland, John L., Houghton, Janet A., Grosveld, Gerard C.
Publicado em 2005

Hedgehog Signaling Regulates Telomerase Reverse Transcriptase in Human Cancer Cells

Por Mazumdar, Tapati, Sandhu, Ranjodh, Qadan, Maha, DeVecchio, Jennifer, Magloire, Victoria, Agyeman, Akwasi, Li, Bibo, Houghton, Janet A.
Publicado em 2013

Targeting autophagy augments the anticancer activity of the histone deacetylase inhibitor SAHA to overcome Bcr-Abl–mediated drug resistance

Por Carew, Jennifer S., Nawrocki, Steffan T., Kahue, Charissa N., Zhang, Hui, Yang, Chunying, Chung, Linda, Houghton, Janet A., Huang, Peng, Giles, Francis J., Cleveland, John L.
Publicado em 2007

Myc regulates aggresome formation, the induction of Noxa, and apoptosis in response to the combination of bortezomib and SAHA

Por Nawrocki, Steffan T., Carew, Jennifer S., Maclean, Kirsteen H., Courage, James F., Huang, Peng, Houghton, Janet A., Cleveland, John L., Giles, Francis J., McConkey, David J.
Publicado em 2008

The Novel Polyamine Analog CGC-11093 Enhances the Anti-Myeloma Activity of Bortezomib

Por Carew, Jennifer S., Nawrocki, Steffan T., Reddy, Venudhar K., Bush, Dorothy, Rehg, Jerold E., Goodwin, Andrew, Houghton, Janet A., Casero, Robert A., Marton, Laurence J., Cleveland, John L.
Publicado em 2008

An antiapoptotic BCL-2 family expression index predicts the response of chronic lymphocytic leukemia to ABT-737

Por Al-harbi, Sayer, Hill, Brian T., Mazumder, Suparna, Singh, Kamini, DeVecchio, Jennifer, Choudhary, Gaurav, Rybicki, Lisa A., Kalaycio, Matt, Maciejewski, Jaroslaw P., Houghton, Janet A., Almasan, Alexandru
Publicado em 2011