Hedgehog Signaling Regulates Telomerase Reverse Transcriptase in Human Cancer Cells

The Hedgehog (HH) signaling pathway is critical for normal embryonic development, tissue patterning and cell differentiation. Aberrant HH signaling is involved in multiple human cancers. HH signaling involves a multi-protein cascade activating the GLI proteins that transcriptionally regulate HH targ...

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Main Authors: Mazumdar, Tapati, Sandhu, Ranjodh, Qadan, Maha, DeVecchio, Jennifer, Magloire, Victoria, Agyeman, Akwasi, Li, Bibo, Houghton, Janet A.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3783395/
https://ncbi.nlm.nih.gov/pubmed/24086482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075253
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