Hedgehog Signaling Regulates Telomerase Reverse Transcriptase in Human Cancer Cells

The Hedgehog (HH) signaling pathway is critical for normal embryonic development, tissue patterning and cell differentiation. Aberrant HH signaling is involved in multiple human cancers. HH signaling involves a multi-protein cascade activating the GLI proteins that transcriptionally regulate HH targ...

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Autores principales: Mazumdar, Tapati, Sandhu, Ranjodh, Qadan, Maha, DeVecchio, Jennifer, Magloire, Victoria, Agyeman, Akwasi, Li, Bibo, Houghton, Janet A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3783395/
https://ncbi.nlm.nih.gov/pubmed/24086482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075253
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