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ATP modulates PTEN subcellular localization in multiple cancer cell lines

The tumour suppressor gene PTEN plays an important somatic role in both hereditary and sporadic breast carcinogenesis. While the role of PTEN's lipid phosphatase activity, as a negative regulator of the cytoplasmic phosphatidylinositol-3-kinase/Akt pathway is well known, it is now well establis...

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Detalhes bibliográficos
Main Authors: Lobo, Glenn P., Waite, Kristin A., Planchon, Sarah M., Romigh, Todd, Houghton, Janet A., Eng, Charis
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2525500/
https://ncbi.nlm.nih.gov/pubmed/18579579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn185
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