Stimulating Retinal Blood Vessel Protection with Hypoxia-Inducible Factor Stabilization: Identification of Novel Small-Molecule Hydrazones to Inhibit Hypoxia-Inducible Factor Proly...

by Sears, Jonathan E., Hoppe, George
Published 2013

Prolyl hydroxylase inhibition during hyperoxia prevents oxygen-induced retinopathy

by Sears, Jonathan E., Hoppe, George, Ebrahem, Quteba, Anand-Apte, Bela
Published 2008

Rank Order of Small Molecule Induced Hypoxiamimesis to Prevent Retinopathy of Prematurity

by Hoppe, George, Bolok, Youstina, McCollum, Leah, Zhang, Jin, Sears, Jonathan E.
Published in Front Cell Dev Biol (2020)

3-Hydroxypyruvate Destabilizes Hypoxia Inducible Factor and Induces Angiostasis

by Singh, Charandeep, Sharma, Amit, Hoppe, George, Song, Weilin, Bolok, Youstina, Sears, Jonathan E.
Published in Invest Ophthalmol Vis Sci (2018)

Hydrodynamic properties of porcine bestrophin-1 in Triton X-100

by Stanton, J. Brett, Goldberg, Andrew F.X., Hoppe, George, Marmorstein, Lihua Y., Marmorstein, Alan D.
Published 2006

IMMUNE TOLERANCE INDUCTION BY APOPTOTIC CELLS REQUIRES CASPASE-DEPENDENT OXIDATION OF HMGB1

by Kazama, Hirotaka, Ricci, Jean-Ehrland, Herndon, John M., Hoppe, George, Green, Douglas R., Ferguson, Thomas A.
Published 2008

Proangiogenic Properties of Thrombospondin-4

by Muppala, Santoshi, Frolova, Ella, Xiao, Roy, Krukovets, Irene, Yoon, Suzy, Hoppe, George, Vasanji, Amit, Plow, Edward, Stenina-Adognravi, Olga
Published in Arterioscler Thromb Vasc Biol (2015)

Comparison of Biphasic vs Static Oxygen Saturation Targets Among Infants With Retinopathy of Prematurity

by Shukla, Ankita, Sonnie, Christine, Worley, Sarah, Sharma, Amit, Howard, Dawn, Moore, Jon, Rodriguez, Ricardo J., Hoppe, George, Sears, Jonathan E.
Published in JAMA Ophthalmol (2019)

Serine and 1-carbon metabolism are required for HIF-mediated protection against retinopathy of prematurity

by Singh, Charandeep, Hoppe, George, Tran, Vincent, McCollum, Leah, Bolok, Youstina, Song, Weilin, Sharma, Amit, Brunengraber, Henri, Sears, Jonathan E.
Published in JCI Insight (2019)

Hyperoxia induces glutamine-fuelled anaplerosis in retinal Müller cells

by Singh, Charandeep, Tran, Vincent, McCollum, Leah, Bolok, Youstina, Allan, Kristin, Yuan, Alex, Hoppe, George, Brunengraber, Henri, Sears, Jonathan E.
Published in Nat Commun (2020)

Comparative systems pharmacology of HIF stabilization in the prevention of retinopathy of prematurity

by Hoppe, George, Yoon, Suzy, Gopalan, Banu, Savage, Alexandria R., Brown, Rebecca, Case, Kelsey, Vasanji, Amit, Chan, E. Ricky, Silver, Randi B., Sears, Jonathan E.
Published in Proc Natl Acad Sci U S A (2016)

Endogenous HMGB1 regulates autophagy

by Tang, Daolin, Kang, Rui, Livesey, Kristen M., Cheh, Chun-Wei, Farkas, Adam, Loughran, Patricia, Hoppe, George, Bianchi, Marco E., Tracey, Kevin J., Zeh, Herbert J., Lotze, Michael T.
Published 2010

Light-induced Oxidation of Photoreceptor Outer Segment Phospholipids Generates Ligands for CD36-mediated Phagocytosis by Retinal Pigment Epithelium: A Potential Mechanism for Modul...

by Sun, Mingjiang, Finnemann, Silvia C., Febbraio, Maria, Shan, Lian, Annangudi, Suresh P., Podrez, Eugene A., Hoppe, George, Darrow, Ruth, Organisciak, Daniel T., Salomon, Robert G., Silverstein, Roy L., Hazen, Stanley L.
Published 2005