Rank Order of Small Molecule Induced Hypoxiamimesis to Prevent Retinopathy of Prematurity

Here we rank order small molecule inhibitors of hypoxia inducible factor (HIF) prolyl hydroxylases (PHDs) using severity of oxygen induced retinopathy (OIR) as an outcome measure. Dose response analyses in cell cultures of hepatoma (Hep3B), retinal Müller cells (MIO-M1) and primary retinal endotheli...

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Udgivet i:Front Cell Dev Biol
Main Authors: Hoppe, George, Bolok, Youstina, McCollum, Leah, Zhang, Jin, Sears, Jonathan E.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Cell and Developmental Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7324656/
https://ncbi.nlm.nih.gov/pubmed/32656210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00488
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