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3-Hydroxypyruvate Destabilizes Hypoxia Inducible Factor and Induces Angiostasis
PURPOSE: Transcriptional analysis of retina protected by hypoxia-inducible factor (HIF) stabilization demonstrates an increase in genes associated with aerobic glycolysis. We hypothesized that since protection is associated with a change in metabolism, oxygen-induced metabolites might transduce oxyg...
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| Publicado no: | Invest Ophthalmol Vis Sci |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Association for Research in Vision and Ophthalmology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6733534/ https://ncbi.nlm.nih.gov/pubmed/30025089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.18-24120 |
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