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3-Hydroxypyruvate Destabilizes Hypoxia Inducible Factor and Induces Angiostasis
PURPOSE: Transcriptional analysis of retina protected by hypoxia-inducible factor (HIF) stabilization demonstrates an increase in genes associated with aerobic glycolysis. We hypothesized that since protection is associated with a change in metabolism, oxygen-induced metabolites might transduce oxyg...
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| Vydáno v: | Invest Ophthalmol Vis Sci |
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| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The Association for Research in Vision and Ophthalmology
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6733534/ https://ncbi.nlm.nih.gov/pubmed/30025089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.18-24120 |
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