Hyperoxia induces glutamine-fuelled anaplerosis in retinal Müller cells

Although supplemental oxygen is required to promote survival of severely premature infants, hyperoxia is simultaneously harmful to premature developing tissues such as in the retina. Here we report the effect of hyperoxia on central carbon metabolism in primary mouse Müller glial cells and a human M...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Singh, Charandeep, Tran, Vincent, McCollum, Leah, Bolok, Youstina, Allan, Kristin, Yuan, Alex, Hoppe, George, Brunengraber, Henri, Sears, Jonathan E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7062830/
https://ncbi.nlm.nih.gov/pubmed/32152301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15066-6
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