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Hyperoxia induces glutamine-fuelled anaplerosis in retinal Müller cells

Although supplemental oxygen is required to promote survival of severely premature infants, hyperoxia is simultaneously harmful to premature developing tissues such as in the retina. Here we report the effect of hyperoxia on central carbon metabolism in primary mouse Müller glial cells and a human M...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Singh, Charandeep, Tran, Vincent, McCollum, Leah, Bolok, Youstina, Allan, Kristin, Yuan, Alex, Hoppe, George, Brunengraber, Henri, Sears, Jonathan E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7062830/
https://ncbi.nlm.nih.gov/pubmed/32152301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15066-6
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