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Rank Order of Small Molecule Induced Hypoxiamimesis to Prevent Retinopathy of Prematurity

Here we rank order small molecule inhibitors of hypoxia inducible factor (HIF) prolyl hydroxylases (PHDs) using severity of oxygen induced retinopathy (OIR) as an outcome measure. Dose response analyses in cell cultures of hepatoma (Hep3B), retinal Müller cells (MIO-M1) and primary retinal endotheli...

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Publicat a:Front Cell Dev Biol
Autors principals: Hoppe, George, Bolok, Youstina, McCollum, Leah, Zhang, Jin, Sears, Jonathan E.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7324656/
https://ncbi.nlm.nih.gov/pubmed/32656210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00488
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