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IMMUNE TOLERANCE INDUCTION BY APOPTOTIC CELLS REQUIRES CASPASE-DEPENDENT OXIDATION OF HMGB1

The mammalian immune system discriminates between modes of cell death, with necrosis often resulting in inflammation and adaptive immunity, while apoptosis tends to be anti-inflammatory, promoting immune tolerance. In many systems immune tolerance can be established through cross presentation of ant...

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Detalhes bibliográficos
Main Authors: Kazama, Hirotaka, Ricci, Jean-Ehrland, Herndon, John M., Hoppe, George, Green, Douglas R., Ferguson, Thomas A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704496/
https://ncbi.nlm.nih.gov/pubmed/18631454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2008.05.013
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