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Hydrodynamic properties of porcine bestrophin-1 in Triton X-100

Bestrophin-1 (Best-1) is an integral membrane protein, defects in which cause Best vitelliform macular dystrophy. Best-1 is proposed to function as a Cl(−) channel and/or a regulator of Ca(++) channels. A tetrameric (or pentameric) stoichiometry has been reported for recombinant best-1. Using a comb...

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Autors principals: Stanton, J. Brett, Goldberg, Andrew F.X., Hoppe, George, Marmorstein, Lihua Y., Marmorstein, Alan D.
Format: Artigo
Idioma:Inglês
Publicat: 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832839/
https://ncbi.nlm.nih.gov/pubmed/16600174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2006.01.024
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