Bestrophin-1 influences transepithelial electrical properties and Ca(2+) signaling in human retinal pigment epithelium

PURPOSE: Mutations in BEST1, encoding Bestrophin-1 (Best1), cause Best vitelliform macular dystrophy (BVMD) and other inherited retinal degenerative diseases. Best1 is an integral membrane protein localized to the basolateral plasma membrane of the retinal pigment epithelium (RPE). Data from numerou...

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Udgivet i:Mol Vis
Main Authors: Marmorstein, Alan D., Kinnick, Tyson R., Stanton, J. Brett, Johnson, Adiv A., Lynch, Ronald M., Marmorstein, Lihua Y.
Format: Artigo
Sprog:Inglês
Udgivet: Molecular Vision 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390793/
https://ncbi.nlm.nih.gov/pubmed/25878489
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