Molecular characterization of neuroprotective activities of plant based products could revive their utilization and lead discovery of new drug candidates for brain diseases

Por Hegde, Muralidhar L.
Publicado em 2014

Oxidized Base Damage and Single-Strand Break Repair in Mammalian Genomes: Role of Disordered Regions and Posttranslational Modifications in Early Enzymes

Por Hegde, Muralidhar L., Izumi, Tadahide, Mitra, Sankar
Publicado em 2012

Early Steps in the DNA Base Excision/Single-Strand Interruption Repair Pathway in Mammalian Cells

Por Hegde, Muralidhar L., Hazra, Tapas K., Mitra, Sankar
Publicado em 2008

Functions of disordered regions in mammalian early base excision repair proteins

Por Hegde, Muralidhar L., Hazra, Tapas K., Mitra, Sankar
Publicado em 2010

RPA PHYSICALLY INTERACTS WITH THE HUMAN DNA GLYCOSYLASE NEIL1 TO REGULATE EXCISION OF OXIDATIVE DNA BASE DAMAGE IN PRIMER-TEMPLATE STRUCTURES

Por Theriot, Corey A., Hegde, Muralidhar L., Hazra, Tapas K., Mitra, Sankar
Publicado em 2010

Oxidative Genome Damage and Its Repair in Neurodegenerative Diseases: Function of Transition Metals as a Double-Edged Sword

Por Hegde, Muralidhar L., Hegde, Pavana M., Rao, K.S.J., Mitra, Sankar
Publicado em 2011

New paradigms in the repair of oxidative damage in human genome: mechanisms ensuring repair of mutagenic base lesions during replication and involvement of accessory proteins

Por Dutta, Arijit, Yang, Chunying, Sengupta, Shiladitya, Mitra, Sankar, Hegde, Muralidhar L.
Publicado no Cell Mol Life Sci (2015)

Human DNA Glycosylase NEIL1’s Interactions with Downstream Repair Proteins Is Critical for Efficient Repair of Oxidized DNA Base Damage and Enhanced Cell Survival

Por Hegde, Muralidhar L., Hegde, Pavana M., Arijit, Dutta, Boldogh, Istvan, Mitra, Sankar
Publicado em 2012

New evidence on α-synuclein and Tau binding to conformation and sequence specific GC* rich DNA: Relevance to neurological disorders

Por Vasudevaraju, P., Guerrero, Erika, Hegde, Muralidhar L., Collen, T. B., Britton, Gabrielle B., Rao, K. S.
Publicado em 2012

A Perspective on Chromosomal Double Strand Break Markers in Mammalian Cells

Por Wang, Haibo, Adhikari, Sanjay, Butler, Brian E., Pandita, Tej K., Mitra, Sankar, Hegde, Muralidhar L.
Publicado no Jacobs J Radiat Oncol (2014)

Norepinephrine Reduces Reactive Oxygen Species (ROS) and DNA Damage in Ovarian Surface Epithelial Cells

Por Patel, Pooja R, Hegde, Muralidhar L, Theruvathu, Jacob, Mitra, Sankar A, Boldogh, Istvan, Sowers, Lawrence
Publicado no J Bioanal Biomed (2015)

Oxidative Genome Damage and Its repair: Implications in Aging and Neurodegenerative Diseases

Por Hegde, Muralidhar L., Mantha, Anil K., Hazra, Tapas K., Bhakat, Kishor K., Mitra, Sankar, Szczesny, Bartosz
Publicado em 2012

Comprehensive mapping of the C-terminus of flap endonuclease-1 reveals distinct interaction sites for five proteins that represent different DNA replication and repair pathways

Por Guo, Zhigang, Chavez, Valerie, Singh, Purnima, Finger, L. David, Hang, Haiying, Hegde, Muralidhar L., Mitra, Sankar, Shen, Binghui
Publicado em 2007

Specific Inhibition of NEIL-initiated Repair of Oxidized Base Damage in Human Genome by Copper and Iron: POTENTIAL ETIOLOGICAL LINKAGE TO NEURODEGENERATIVE DISEASES

Por Hegde, Muralidhar L., Hegde, Pavana M., Holthauzen, Luis M. F., Hazra, Tapas K., Rao, K. S. Jagannatha, Mitra, Sankar
Publicado em 2010

Enhancement of NEIL1 Protein-initiated Oxidized DNA Base Excision Repair by Heterogeneous Nuclear Ribonucleoprotein U (hnRNP-U) via Direct Interaction

Por Hegde, Muralidhar L., Banerjee, Srijita, Hegde, Pavana M., Bellot, Larry J., Hazra, Tapas K., Boldogh, Istvan, Mitra, Sankar
Publicado em 2012

Revisiting Metal Toxicity in Neurodegenerative Diseases and Stroke: Therapeutic Potential

Por Mitra, Joy, Vasquez, Velmarini, Hegde, Pavana M, Boldogh, Istvan, Mitra, Sankar, Kent, Thomas A, Rao, Kosagi S, Hegde, Muralidhar L
Publicado no Neurol Res Ther (2014)

Activation of cellular signaling by 8-oxoguanine DNA glycosylase-1-initiated DNA base excision repair

Por German, Peter, Szaniszlo, Peter, Hajas, Gyorgy, Radak, Zsolt, Bacsi, Attila, Hazra, Tapas K., Hegde, Muralidhar L., Ba, Xueqing, Boldogh, Istvan
Publicado em 2013

New Perspectives on Oxidized Genome Damage and Repair Inhibition by Pro-Oxidant Metals in Neurological Diseases

Por Mitra, Joy, Guerrero, Erika N., Hegde, Pavana M., Wang, Haibo, Boldogh, Istvan, Rao, Kosagi Sharaf, Mitra, Sankar, Hegde, Muralidhar L.
Publicado em 2014

Chronic Oxidative Damage together with Genome Repair Deficiency in the Neurons is a Double Whammy for Neurodegeneration: Is Damage Response Signaling a Potential Therapeutic Target...

Por Wang, Haibo, Dharmalingam, Prakash, Vasquez, Velmarini, Mitra, Joy, Boldogh, Istvan, Rao, K. S., Kent, Thomas A., Mitra, Sankar, Hegde, Muralidhar L.
Publicado no Mech Ageing Dev (2016)

Activation of Ras Signaling Pathway by 8-Oxoguanine DNA Glycosylase Bound to Its Excision Product, 8-Oxoguanine

Por Boldogh, Istvan, Hajas, Gyorgy, Aguilera-Aguirre, Leopoldo, Hegde, Muralidhar L., Radak, Zsolt, Bacsi, Attila, Sur, Sanjiv, Hazra, Tapas K., Mitra, Sankar
Publicado em 2012