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RPA PHYSICALLY INTERACTS WITH THE HUMAN DNA GLYCOSYLASE NEIL1 TO REGULATE EXCISION OF OXIDATIVE DNA BASE DAMAGE IN PRIMER-TEMPLATE STRUCTURES
The human DNA glycosylase NEIL1, activated during the S-phase, has been shown to excise oxidized base lesions in single-strand DNA substrates. Furthermore, our previous work demonstrating functional interaction of NEIL1 with PCNA and flap endonuclease 1 (FEN1) suggested its involvement in replicatio...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2883689/ https://ncbi.nlm.nih.gov/pubmed/20338831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2010.02.014 |
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