Prereplicative repair of oxidized bases in the human genome is mediated by NEIL1 DNA glycosylase together with replication proteins

Base oxidation by endogenous and environmentally induced reactive oxygen species preferentially occurs in replicating single-stranded templates in mammalian genomes, warranting prereplicative repair of the mutagenic base lesions. It is not clear how such lesions (which, unlike bulky adducts, do not...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Hegde, Muralidhar L., Hegde, Pavana M., Bellot, Larry J., Mandal, Santi M., Hazra, Tapas K., Li, Guo-Min, Boldogh, Istvan, Tomkinson, Alan E., Mitra, Sankar
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3746843/
https://ncbi.nlm.nih.gov/pubmed/23898192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1304231110
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados