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Mutator Phenotype of Mammalian Cells Due to Deficiency of NEIL1 DNA Glycosylase, An Oxidized Base-Specific Repair Enzyme
The recently characterized NEIL1 and NEIL2 are distinct from the previously characterized mammalian DNA glycosylases (OGG1 and NTH1) involved in repair of oxidized bases because of the NEILs’ preference for excising base lesions from single-stranded DNA present in bubble and fork structures. OGG1 an...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2567110/ https://ncbi.nlm.nih.gov/pubmed/18495559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2008.03.025 |
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