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Complexities of the DNA Base Excision Repair Pathway for Repair of Oxidative DNA Damage

Oxidative damage represents the most significant insult to organisms because of continuous production of the reactive oxygen species (ROS) in vivo. Oxidative damage in DNA, a critical target of ROS, is repaired primarily via the base excision repair (BER) pathway which appears to be the simplest amo...

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Bibliographic Details
Published in:Environ Mol Mutagen
Main Authors: Mitra, Sankar, Boldogh, Istvan, Izumi, Tadahide, Hazra, Tapas K.
Format: Artigo
Language:Inglês
Published: 2001
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4927302/
https://ncbi.nlm.nih.gov/pubmed/11746753
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