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Early Steps in the DNA Base Excision/Single-Strand Interruption Repair Pathway in Mammalian Cells
Base excision repair (BER) is an evolutionarily conserved process for maintaining genomic integrity by eliminating several dozen damaged (oxidized or alkylated) or inappropriate bases that are generated endogenously or induced by genotoxicants, predominantly, reactive oxygen species (ROS). BER invol...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2692221/ https://ncbi.nlm.nih.gov/pubmed/18166975 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2008.8 |
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