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Acetylation of Human 8-Oxoguanine-DNA Glycosylase by p300 and Its Role in 8-Oxoguanine Repair In Vivo

The human 8-oxoguanine-DNA glycosylase 1 (OGG1) is the major DNA glycosylase responsible for repair of 7,8-dihydro-8-oxoguanine (8-oxoG) and ring-opened fapyguanine, critical mutagenic DNA lesions that are induced by reactive oxygen species. Here we show that OGG1 is acetylated by p300 in vivo predo...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bhakat, Kishor K., Mokkapati, Sanath K., Boldogh, Istvan, Hazra, Tapas K., Mitra, Sankar
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2006
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1430230/
https://ncbi.nlm.nih.gov/pubmed/16478987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.5.1654-1665.2006
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