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Repair of hydantoins, one electron oxidation product of 8-oxoguanine, by DNA glycosylases of Escherichia coli

8-Oxoguanine (8-oxoG), induced by reactive oxygen species and arguably one of the most important mutagenic DNA lesions, is prone to further oxidation. Its one-electron oxidation products include potentially mutagenic guanidinohydantoin (Gh) and spiroiminodihydantoin (Sp) because of their mispairing...

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Detalhes bibliográficos
Main Authors: Hazra, Tapas K., Muller, James G., Manuel, Raymond C., Burrows, Cynthia J., Lloyd, R. Stephen, Mitra, Sankar
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC37251/
https://ncbi.nlm.nih.gov/pubmed/11328881
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