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Mutator Phenotype of Mammalian Cells Due to Deficiency of NEIL1 DNA Glycosylase, An Oxidized Base-Specific Repair Enzyme

The recently characterized NEIL1 and NEIL2 are distinct from the previously characterized mammalian DNA glycosylases (OGG1 and NTH1) involved in repair of oxidized bases because of the NEILs’ preference for excising base lesions from single-stranded DNA present in bubble and fork structures. OGG1 an...

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書誌詳細
主要な著者: Maiti, Amit K., Boldogh, Istvan, Spratt, Heidi, Mitra, Sankar, Hazra, Tapas K.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567110/
https://ncbi.nlm.nih.gov/pubmed/18495559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2008.03.025
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