The C-terminal Domain (CTD) of Human DNA Glycosylase NEIL1 Is Required for Forming BERosome Repair Complex with DNA Replication Proteins at the Replicating Genome: DOMINANT NEGATIVE FUNCTION OF THE CTD

The human DNA glycosylase NEIL1 was recently demonstrated to initiate prereplicative base excision repair (BER) of oxidized bases in the replicating genome, thus preventing mutagenic replication. A significant fraction of NEIL1 in cells is present in large cellular complexes containing DNA replicati...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Hegde, Pavana M., Dutta, Arijit, Sengupta, Shiladitya, Mitra, Joy, Adhikari, Sanjay, Tomkinson, Alan E., Li, Guo-Min, Boldogh, Istvan, Hazra, Tapas K., Mitra, Sankar, Hegde, Muralidhar L.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
DNA and Chromosomes
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4543652/
https://ncbi.nlm.nih.gov/pubmed/26134572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.642918
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