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The C-terminal Domain (CTD) of Human DNA Glycosylase NEIL1 Is Required for Forming BERosome Repair Complex with DNA Replication Proteins at the Replicating Genome: DOMINANT NEGATIVE FUNCTION OF THE CTD

The human DNA glycosylase NEIL1 was recently demonstrated to initiate prereplicative base excision repair (BER) of oxidized bases in the replicating genome, thus preventing mutagenic replication. A significant fraction of NEIL1 in cells is present in large cellular complexes containing DNA replicati...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Hegde, Pavana M., Dutta, Arijit, Sengupta, Shiladitya, Mitra, Joy, Adhikari, Sanjay, Tomkinson, Alan E., Li, Guo-Min, Boldogh, Istvan, Hazra, Tapas K., Mitra, Sankar, Hegde, Muralidhar L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4543652/
https://ncbi.nlm.nih.gov/pubmed/26134572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.642918
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