The C-terminal Domain (CTD) of Human DNA Glycosylase NEIL1 Is Required for Forming BERosome Repair Complex with DNA Replication Proteins at the Replicating Genome: DOMINANT NEGATIVE FUNCTION OF THE CTD

The human DNA glycosylase NEIL1 was recently demonstrated to initiate prereplicative base excision repair (BER) of oxidized bases in the replicating genome, thus preventing mutagenic replication. A significant fraction of NEIL1 in cells is present in large cellular complexes containing DNA replicati...

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Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Hegde, Pavana M., Dutta, Arijit, Sengupta, Shiladitya, Mitra, Joy, Adhikari, Sanjay, Tomkinson, Alan E., Li, Guo-Min, Boldogh, Istvan, Hazra, Tapas K., Mitra, Sankar, Hegde, Muralidhar L.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2015
Teme:
DNA and Chromosomes
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4543652/
https://ncbi.nlm.nih.gov/pubmed/26134572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.642918
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