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Human DNA Glycosylase NEIL1’s Interactions with Downstream Repair Proteins Is Critical for Efficient Repair of Oxidized DNA Base Damage and Enhanced Cell Survival

NEIL1 is unique among the oxidatively damaged base repair-initiating DNA glycosylases in the human genome due to its S phase-specific activation and ability to excise substrate base lesions from single-stranded DNA. We recently characterized NEIL1’s specific binding to downstream canonical repair an...

詳細記述

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書誌詳細
主要な著者: Hegde, Muralidhar L., Hegde, Pavana M., Arijit, Dutta, Boldogh, Istvan, Mitra, Sankar
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3733129/
https://ncbi.nlm.nih.gov/pubmed/23926464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom2040564
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